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KMID : 1134820090380070846
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Journal of the Korean Society of Food Science and Nutrition
2009 Volume.38 No. 7 p.846 ~ p.851
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Effects of Puerariae Flos on Antioxidative Activities and Lipid Levels in Hyperlipidemic Sprague-Dawley Rats
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Park Gun-Jin
Lee Hyung-Woo
Park Byong-Ryol
Park Sung-Jin
Kim Jong-Dai
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Abstract
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This study was carried out to investigate the effects of Puerariae Flos extracts on antioxidative potential, free radical generation and the lipid levels in rats. Sprague-Dawley rats were divided into 2 diet groups: AIN-76 diet (control group) and modified AIN-76 diet (cholesterol 0.5%) with 0.5% Puerariae Flos extracts for 4 weeks. Body weight and feed efficiency ratios from both groups were not significantly different. Antioxidative potentials significantly increased in the group fed Puerariae Flos extracts compared to control group (p＜0.05). However, there was no difference in free radical generation. The weight of organs, such as heart, kidney, liver, and spleen, in rats were not different in both groups. The ratio HDL cholesterol to total cholesterol in the Puerariae Flos group was significantly higher than in the control group, while the other serum lipid parameters (total cholesterol, HDL cholesterol, triglyceride, and phospholipids) were not different between the two groups. These results imply that supplementation of Puerariae Flos extracts may beneficially contribute to improve antioxidant potential and to decrease the lipid levels in the blood.
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KEYWORD
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Puerariae Flos, total cholesterol, HDL-cholesterol, triglyceride, antioxidative activities
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